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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
10.91
Human Site:
S143
Identified Species:
18.46
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
S143
F
K
W
M
R
D
D
S
E
L
T
T
Y
S
S
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
S105
S
E
L
T
T
Y
S
S
E
Y
K
Y
I
I
P
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
L89
W
M
R
D
G
R
E
L
T
T
Y
S
S
E
Y
Dog
Lupus familis
XP_547004
2144
235913
R108
Y
R
C
V
V
R
N
R
M
G
A
L
L
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
S125
F
K
W
I
R
N
D
S
E
L
T
T
Y
S
S
Rat
Rattus norvegicus
XP_001073292
2181
239558
S113
F
K
W
I
R
N
D
S
E
L
T
A
Y
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
Y105
K
S
E
V
Q
V
A
Y
M
G
D
F
M
A
A
Chicken
Gallus gallus
Q8AV58
2169
239459
K105
T
T
Y
S
S
E
Y
K
Y
I
I
P
A
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
M101
A
E
I
Q
V
A
Y
M
G
D
F
I
D
N
D
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
V112
Y
R
W
L
K
D
G
V
P
V
G
D
F
S
S
Honey Bee
Apis mellifera
XP_623565
2176
242722
E105
R
I
Q
S
T
R
R
E
D
A
G
V
Y
H
C
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
D117
V
R
S
K
Y
L
D
D
F
D
A
S
D
E
S
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
A129
T
M
V
S
A
G
A
A
K
I
L
T
C
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
13.3
0
0
N.A.
86.6
80
N.A.
0
0
N.A.
0
0
26.6
6.6
13.3
6.6
P-Site Similarity:
100
20
20
26.6
N.A.
100
93.3
N.A.
26.6
20
N.A.
13.3
0
66.6
13.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
15
8
0
8
15
8
8
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
0
0
0
8
0
15
29
8
8
15
8
8
15
0
8
% D
% Glu:
0
15
8
0
0
8
8
8
29
0
0
0
0
15
0
% E
% Phe:
22
0
0
0
0
0
0
0
8
0
8
8
8
0
0
% F
% Gly:
0
0
0
0
8
8
8
0
8
15
15
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
8
15
0
0
0
0
0
15
8
8
8
8
0
% I
% Lys:
8
22
0
8
8
0
0
8
8
0
8
0
0
0
0
% K
% Leu:
0
0
8
8
0
8
0
8
0
22
8
8
8
8
0
% L
% Met:
0
15
0
8
0
0
0
8
15
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
15
8
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
15
% P
% Gln:
0
0
8
8
8
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
8
22
8
0
22
22
8
8
0
0
0
0
0
0
8
% R
% Ser:
8
8
8
22
8
0
8
29
0
0
0
15
8
29
36
% S
% Thr:
15
8
0
8
15
0
0
0
8
8
22
22
0
0
0
% T
% Val:
8
0
8
15
15
8
0
8
0
8
0
8
0
0
0
% V
% Trp:
8
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
8
0
8
8
15
8
8
8
8
8
29
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _